Which metal alloy component is commonly associated with nickel allergy?

Which metal alloy component is commonly associated with nickel allergy?

• A. Chromium
• B. Nickel
• C. Cobalt
• D. Titanium

Answer: (B)

Nickel allergy is driven by a common contact allergen in dental materials. Nickel-containing alloys are widely used to improve strength and workability, and nickel ions can be released in the oral environment, acting as haptens that bind proteins and trigger a type IV hypersensitivity reaction mediated by T cells. This is why nickel is the metal most frequently linked to allergic reactions to dental alloys. Chromium and cobalt can also cause allergic responses, but far less commonly than nickel, while titanium is generally well tolerated. So the component most associated with nickel allergy is nickel.

Nickel allergy is driven by a common contact allergen in dental materials. Nickel-containing alloys are widely used to improve strength and workability, and nickel ions can be released in the oral environment, acting as haptens that bind proteins and trigger a type IV hypersensitivity reaction mediated by T cells. This is why nickel is the metal most frequently linked to allergic reactions to dental alloys. Chromium and cobalt can also cause allergic responses, but far less commonly than nickel, while titanium is generally well tolerated. So the component most associated with nickel allergy is nickel.